In a study with the National Library of Medicine National Institutes of Health, oral manifestations in vitamin B12 deficiency patients was analysed.
The study noted: “Vitamin B12 is one of important nutritional components that affect oral health.
“The purpose of this study was to compare clinical features of vitamin B12 deficiency patients with a history of gastrectomy to those without a history of gastrectomy.
“Patients’ chief complaints, oral manifestations, blood examination results, and past medical histories were reviewed.”
The study concluded that lacking in vitamin B12 can cause a variety of oral manifestations with tongue pain being the main complaint.